Treatment of stomach and intestinal ulcers, GERD/ gastro-esophageal reflux disease, erosive esophagitis, heartburn (acid regurgitation from stomach up to the mouth), and Zollinger-Ellison Syndrome. Used in combination with other drugs to treat stomach infections caused by bacteria H. pylori. For the prevention of ulcer in patients who need to take NSAIDs/ nonsteroidal anti-inflammatory drugs.

Used in the conditions where inhibition of gastric acid secretion may be beneficial, including aspiration syndromes, dyspepsia, gastroesophageal reflux disease and the Zollinger-Ellison syndrome.